Renal Disorders

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Renasight is a test to determine if there is a genetic cause for an individual's kidney disease or if there is an increased hereditary risk due to family history. The test uses a blood or saliva sample to test 385 genes associated with chronic kidney disease.

Renal Disorders

Renal Disorders

Congenital Renal Disease

Childhood Nephrotic Syndrome Learn More

What is Paediatric Nephrotic Syndrome?
The disorder known as childhood nephrotic syndrome is typically brought on by damage to the blood-filtering kidney cells' small blood capillaries. Protein in blood is retained by healthy arteries and is essential for preserving the body's fluid equilibrium. When these arteries are destroyed, the result is nephrotic syndrome, which causes excessively high levels of blood protein to be expelled in urine. Nephrotic syndrome mostly affects children between the ages of 1 and 5 years, while it can also affect children of all ages and adults.

Chronic Renal Condition

Chronic Kidney Disease Learn More

Description of Chronic Kidney Disease
A disorder called chronic kidney disease (CKD), commonly referred to as chronic kidney failure, is marked by a progressive decline in kidney function. Only a few indications or symptoms may be present in the early stages of CKD nevertheless, over the course of several years, there is a slow and cumulative decrease of kidney function that may eventually lead to permanent kidney failure. Dangerous quantities of waste and fluids can quickly accumulate in the body when renal failure progresses with severe impairment of kidney function.

Glomerulal Conditions

Chronic Glomerulonephritis Learn More

How do you define chronic glomerulonephritis?
Glomerulonephritis is a set of conditions that cause inflammation in the kidney's blood-filtering organs and cause damage to them. Glomerulonephritis can arise on its own or in conjunction with other diseases like lupus or diabetes. Chronic glomerulonephritis is glomerulonephritis that develops gradually. The kidneys may suffer irreparable damage if the glomeruli are severely or repeatedly inflamed.

Focal Segmental Glomerulosclerosis Learn More

The definition of focal segmental glomerulosclerosis
A disorder known as Focal Segmental Glomerulosclerosis (FSGS) causes the kidney to generate scar tissue. Scar tissue harms the kidney's sections responsible for removing waste from blood, which results in ineffective blood filtration and nutritional loss. FSGS can be divided into two types: primary FSGS and secondary FSGS, depending on the causes. Primary FSGS, which develops without a known cause, results in abnormalities in the composition or operation of some kidney cells. Certain illnesses, such as diabetes, obesity, infections, or drug toxicity, are the root cause of secondary FSGS.

IgA Nephropathy Learn More

What Exactly Is IgA Nephropathy?
Immunoglobulin A (IgA) nephropathy is a condition brought on by the buildup of this antibody in the blood. This could result in localised inflammation that impairs kidney function by affecting waste elimination and causing the excretion of protein and blood in the urine. The rate of advancement can differ from person to person, but this ailment typically advances slowly. Although there is no known treatment for IgA nephropathy, certain drugs and preventative actions, such as keeping blood pressure and cholesterol levels within normal ranges, can help manage the disease's progression. Men are at least twice as likely as women to develop IgA nephropathy, which is more prevalent among Caucasians and Asians.

Idiopathic Membranous Nephropathy Learn More

Description of Idiopathic Membranous Nephropathy
Damage to and thickening of the tiny blood capillaries in the kidneys that filter waste from the blood results in idiopathic membranous nephropathy. Proteinuria, which can cause damaged blood vessels to leak protein into the urine, may cause long-term kidney damage. Although the precise cause of this syndrome is unknown, it is thought to be brought on by cancer, autoimmune diseases, or specific drugs. Membranous nephropathy is also more prone to develop due to specific hereditary causes.

Endocrine & Metabolic Disorders

Hyperurecaemia Learn More

Defining hyperuricemia
An increased level of uric acid in the blood is referred to as hyperuricemia. There are instances when the body produces more uric acid than it can process. This may happen as a result of certain disorders or the breakdown of excess purine, which is present in some diets.

Hypomagnesemia Learn More

What Exactly Is Hypomagnesemia?
Low levels of magnesium are present in the serum in a condition known as hypomagnesemia. This is mostly brought on by decreased gastrointestinal absorption of magnesium and increased renal magnesium loss. Along with other electrolyte problems like hypocalcemia (low blood calcium levels), hypokalemia (low blood potassium levels), or both, hypomagnesemia can also happen.

Systemic Lupus

Lupus Nephritis Learn More

lupus nephritis definition
Lupus, also known as systemic lupus erythematosus (SLE), is an autoimmune condition in which the body's immune system unintentionally targets healthy cells and tissues. Lupus nephritis is the medical term for when lupus affects the kidneys. Damage to the small blood veins in the kidneys that filter waste is what causes this illness. The injury causes the excretion of protein or blood in the urine. About 50% of lupus patients develop lupus nephritis. The prevalence of lupus nephritis is higher in men than in women.

Inherited Renal Conditions

Polycystic Kidney Disease Learn More

Polycystic Kidney Disease Explanation
Clusters of cysts form inside the kidneys as a result of a genetic disorder known as polycystic kidney disease, which can cause kidney damage. Until the cysts grow to a size that can significantly impair normal kidney function, they might not first appear to be an issue. The size of the kidneys may also rise as a result of the cyst formation.

Urinary Calculi

Renal Calculi Learn More

What Does Renal Calculi Mean?
Kidney stones, often referred to as renal calculi, develop when minerals and salts in the urine are concentrated and oversaturated. The minerals and salts that make up the stones might form in the kidneys or in other regions of the urinary system. The majority of stones are mostly composed of calcium oxalate. Different renal calculi can develop when the pH of the urine varies. Uric acid or cystine stones develop when the urine is more acidic, whereas calcium and phosphate-containing stones do so when it is more alkaline.

Congenital Renal and Genitourinary Condition

Vesicoureteric Reflux Learn More

What Is Vesicoureteric Reflux
Everybody's urine flows unilaterally under normal circumstances, from the kidneys through the ureters to the bladder. Vesicoureteric Reflux (VUR), on the other hand, is a disorder in which urine backflows from the bladder to the ureters or even the kidneys. This disorder, which is most prevalent in infants and young children, increases the risk of kidney damage and urinary tract infections.

Description of Test

Your kidneys are part of your urinary system. The two kidneys sit in the back of your abdomen just below your ribcage. They help your body filter waste materials and expel them as urine.

Your kidneys are also vital for producing:

  • Hormones that maintain blood pressure.
  • Red blood cells, which carry oxygen throughout your body.
  • Vitamin D, which maintains bone and muscle health.
  • The Genetic test can give you useful information for managing diseases
  • Identify the underlying cause of the illness and aid in predicting its course
  • By using test results to guide more specialised actions, you can alter the course of treatment.
  • Also, inform family members who might be susceptible to renal disease.

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